The name or term Optimus Prime refers to more than one character or idea. For a list of other meanings, see Optimus Prime (disambiguation).
- Optimus Prime is a Transformer from the Universe war.

Optimus Prime's clone being tortured.
Optimus Prime was the leader of Autobot in an alternate universe. He was among the first to fall in Megazarak's genocidal rampage. Megazarak let his remains to rust on the shores of the Rust Sea. Unicron used his remains to clone his herald, Nemesis Prime. Balancing Act, Part 2